Targeting human liver cancer cells with lactobionic acid-G (4)-PAMAM-FITC sorafenib loaded dendrimers
RM Iacobazzi, L Porcelli, AA Lopedota… - International journal of …, 2017 - Elsevier
… line HepG-2 compared non-expressing HLE cells. Ac-La-G(4)-PAMAM-FITC dendrimer
loaded with sorafenib was stable and showed sustained sorafenib release. As evidenced by the …
loaded with sorafenib was stable and showed sustained sorafenib release. As evidenced by the …
Ligand-mediated Targeted Drug Delivery Approaches against Hepatocellular Carcinoma
… Sorafenib-loaded lactobionic acid conjugated G(4)PAMAM-FITC dendrimers were
investigated by Iacobazzi and co-workers for the targeting of human liver cancer cells. …
investigated by Iacobazzi and co-workers for the targeting of human liver cancer cells. …
Exploiting the bioengineering versatility of lactobionic acid in targeted nanosystems and biomaterials
S Alonso - Journal of Controlled Release, 2018 - Elsevier
… dendrimer-based systems targeting liver cancer cells. LBA-… rate of loaded DOX as well as
higher liver cancer cell targeting ability … of promising anti-cancer drugs such as sorafenib [37] or …
higher liver cancer cell targeting ability … of promising anti-cancer drugs such as sorafenib [37] or …
Targeted delivery of miR-218 via decorated hyperbranched polyamidoamine for liver cancer regression
AM Elfiky, RH Mohamed, FEZ Abd EL-Hakam… - International Journal of …, 2021 - Elsevier
… high loading efficiency of DNA and enhances the cellular … to the widely used PAMAM
dendrimer (G4) which needs multi-… LA moieties against human liver carcinoma cell line (HepG2). …
dendrimer (G4) which needs multi-… LA moieties against human liver carcinoma cell line (HepG2). …
Nanotechnology based approach for hepatocellular carcinoma targeting
… the liver tumor cells, therefore, increase selective targeting of … and lactobionic acid (MSN-CS-LA
nanocarriers) to target … have shown that sorafenib loaded with dendrimer exhibits superi…
nanocarriers) to target … have shown that sorafenib loaded with dendrimer exhibits superi…
Surface functionalized dendrimers as controlled-release delivery nanosystems for tumor targeting
… in cancer treatment, iii) surface functionalization of dendrimer … loaded dendrimer by
accumulation of gemcitabine in tumor … Sorafenib encapsulated Ac-La-G (4.0)-PAMAM-FITC …
accumulation of gemcitabine in tumor … Sorafenib encapsulated Ac-La-G (4.0)-PAMAM-FITC …
Multifunctional nanoplatform based on star-shaped copolymer for liver cancer targeting therapy
X Gong, Y Zheng, G He, K Chen, X Zeng, Z Chen - Drug Delivery, 2019 - Taylor & Francis
… Lactobionic acid (LA), which is composed of one molecule of … ), allowing the targeted delivery
of drugs to liver cancer cells. … F-loaded NPs, human hepatocellular carcinoma cells, HepG2…
of drugs to liver cancer cells. … F-loaded NPs, human hepatocellular carcinoma cells, HepG2…
Expatiating the pivotal role of Dendrimers as emerging nanocarrier for management of Liver Disorders
… Patent literature status related to application of dendrimers in liver disorders … Targeting
human liver cancer cells with lactobionic acid-G (4)-PAMAM-FITC sorafenib loaded dendrimers. Int…
human liver cancer cells with lactobionic acid-G (4)-PAMAM-FITC sorafenib loaded dendrimers. Int…
Biotin functionalized PEGylated poly (amidoamine) dendrimer conjugate for active targeting of paclitaxel in cancer
… ) dendrimers of generation 4 (G4) to deliver paclitaxel (PTX), a poorly soluble anti-cancer
agent precisely to cancer cells … of PTX to cancer cells than non-targeted dendrimer or free drug. …
agent precisely to cancer cells … of PTX to cancer cells than non-targeted dendrimer or free drug. …
Preparation and evaluation of folate-decorated human serum albumin nanoparticles for the targeted delivery of sorafenib to enhance antihepatocarcinoma efficacy
W Gao, X Jia, J Wu, Y Song, J Yin, M Zhang… - Journal of Drug Delivery …, 2019 - Elsevier
… -human serum albumin-sorafenib nanoparticles (FA-HSA-SRF-NPs) to improve the active-targeting
to liver tumor cells … sorafenib-loaded human serum albumin nanoparticles with active-…
to liver tumor cells … sorafenib-loaded human serum albumin nanoparticles with active-…